Immune responses after fractional doses of inactivated poliovirus vaccine using newly developed intradermal jet injectors: A randomized controlled trial in Cuba

Author: Sonia Resik, Alina Tejeda, Ondrej Mach, Magile Fonseca, Manuel Diaz, Nilda Alemany, Gloria Garcia, Lai Heng Hung, Yenisleydis Martinez, Roland Sutter


The World Health Organization recommends that, as part of the new polio endgame, a dose of inactivated poliovirus vaccine (IPV) be introduced by the end of 2015 in all countries using only oral poliovirus vaccine (OPV). Administration of fractional dose (1/5th of full dose) IPV (fIPV) intradermally may reduce costs, but its administration is cumbersome with BCG needle and syringe. We evaluated performance of two newly developed intradermal-only jet injectors and compared the immune response induced by fIPV with that induced by full-dose IPV.


Type Journal article
Language English
Country Not Specified
Journal Vaccine
Volume 33
Publisher Elsevier
Year 2014
Disease , Inactivated poliovirus vaccine , Intradermal administration , Poliomyelitis
Added by Marilyn Kelly
Added on 23 February 2017 10:41:32
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