Thanks colleagues for helping to organize this session--it was very enlightening! Temperature is an invisible property--I think the charting of actual temperature data is a powerful tool for triggering a new understanding of what happens in a refrigerator. Are there country CCE managers out there who are using temperature charts as a regular tool for communication and problem solving? Would love to hear about your experience!
Hi Joanie
Several years I unsuccessfully tried to promote using MKT temperature to see how a temperature excursion would affect the life of a vaccine. Calculating the MKT temperature in combination with the Arrenhenius graphs you could find the percent of life lost for vaccines of differing sensitivities for the temperature profile in your example. I don't think there is another way to quantitatively see the effect of an excursion on the life of a vaccine.
Since the the loss of life increases exponentialy at higher temperatures it is hard to visually see the consequences of a temperature excursion by looking at a graph. There may be instances, for example where a system has a bad battery and each night the temperature would go above 10 Deg C. Using an MKT analysis you could find that the excursion has a negligible effect on the life of a vaccine and fixing the battery could become a lower priority.
Larry Schlussler PhD
Sun Frost
My new email address [email protected]
I think routinely (also) using MKT is a great idea. DHIS2 would like to develop a mobile app for connecting EMS (Equipment Monitoring System) compatible cold chain equipment to a mobile phone via Bluetooth and use the 10-minute readouts for (also) calculating the MKT in the mobile app and displaying it in analytics tools. A single value which can summarize hundreds or thousands of temperature values is a dream come true for analysts and every-day users which is quicker and easier to interpret than a long time series.
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