we wish to share the following findings for needful.
India begins study on BCG vaccine impact on Covid-19
“Two recently released studies, one in India and the other in US concluded that the inexpensive and widely used BCG vaccine, which protects against childhood tuberculosis, could also prevent severe infection and deaths in some Covid-19 patients”.
Based on the observation that “those who got BCG vaccination, not just in India but in other countries, are more protected than those who were not [vaccinated]…… BCG-mediated immune response would help in lowering both incidence and severity of infection – can be a “hypothesis”.
The Indian Council of Medical Research-National Institute for Research in Tuberculosis (ICMR-NIRT) has initiated a multi-centric study to see if tuberculosis vaccine -- bacille Calmette Guerin (BCG) can reduce the severity of Covid-19 among people aged 60 and above residing in hot spots for SARS-CoV-2, the virus that causes the disease…….
The study will involve around 1,000 healthy volunteers above 60 years of age in six states that have reported a high Covid-19 disease burden so far.
On reading the above people started voluntary BCG vaccination.
But vaccine needs to be “administered properly” in potent condition (VVM in useable stage, correct diluent in correct quantity and temperature, correct dosage, right route – intradermally which yields a wheal of around 10mm with 0.1mL vaccine). BCG is a live attenuated vaccine, following administration, granulomatous reaction occurs at the site of administration and pass through all six stages from erythema, nodule, pustule, ulcer, crust and a characteristic raised scar formation in 4-6 weeks period in that sequence.
The “wheal” of ~10mm on administering 0.1mL of BCG vaccine. Similar “wheal” can be seen on administering 0.1mL Tuberculin reagent, 0.1mL fIPV intradermally. Vaccinator should have the proper skill to administer intradermally; especially in children – administering to adults is comparatively easy.
Induration of >20mm following vaccination which remained for > a week.
The scar of 3 different vaccinees following 42 days.
We wish to follow the scars for a few more weeks to document the dry scar (see document attached).
If the “Rights” of vaccination are not adhered, immunogenic scar may not develop defeating the objective of vaccination as we are not able to see these stages / scar in the newborns vaccinated in the private sector (vaccine deprived of VVM etc). Hope the study will take care of the proper administration.
The PDF depicting the photos is attached for reference.
Holla n Team
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