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VIEW-hub is an easy to use repository for the most relevant and recent vaccine data, covering topics such as Vaccine Introduction & Use, Immunization Equity, Vaccine Preventable Disease Burden, and...
In accordance with its mandate to provide guidance to Member States on health policy matters, WHO publishes vaccine position papers providing global vaccine and immunization recommendations for...
UNIVAC is a single universal vaccine impact and cost-effectiveness decision support model with a standardized, accessible Excel-based (now based in R), interface and a familiar set of input steps and...
The Consortium aims to deliver a more sustainable, efficent, and transparent approach to generating disease burden and vaccine impact estimates. It works on aggregating the estimates across a...
This document is intended for use by national immunization programme managers and immunization partners to inform the policy discussions and operational aspects for the introduction of HPV vaccine...
This manual describes approaches to measuring pneumococcal and Hib conjugate vaccine impact and a framework for determining the best methodology for measuring that impact for different country or...
WHO recommends that Haemophilus influenzae type B (Hib) vaccine be included in routine infant immunization programmes for all children, as appropriate to national capacities and priorities. This...
The main objective of this tool is to provide a methodology for countries to rapidly assess the burden of Hib disease using as much local data as possible. This document includes information on how...
This report details the danger of freezing vaccine as illustrated by epidemics of whooping cough among children who have received the pertussis vaccine. One factor contributing to the delivery of...
Since the global Expanded Program on Immunization (EPI) was launched in 1974, vaccination against six diseases (tuberculosis, polio, diphtheria, tetanus, pertussis, and measles) has prevented...
Complex humanitarian emergencies affect 40–60 million people annually and are a growing public health concern worldwide. Despite efforts to provide medical and public health services to populations...
PURPOSE:
The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. It was questioned if this is a safe vaccine. Therefore, we...
The international community has successfully promoted childhood vaccination as an essential public health intervention. This has been accomplished through efforts such as the World Health...
Otitis media is a common childhood infection of the middle ear and a major cause of morbidity. This multifactorial disease manifests as a spectrum of clinical syndromes from uncomplicated acute...
Haemophilus influenzae type b (Hib) conjugate vaccine, delivered as a three-dose series without a booster, was introduced into the childhood vaccination programme in Kenya in 2001. The duration of...
The optimal long-term vaccination strategies to provide population-level protection against serogroup A Neisseria meningitidis (MenA) are unknown. We developed an age-structured mathematical model of...
Most surveyed parents believe vaccines are important for child health and rate disease prevention higher than number of injections entailed. Providers underestimate the importance of some vaccines to...
The Journal of Infectious Diseases supplement rightly focuses on the notion of integrated healthcare, which has a long history in public health. Integrated healthcare has been proposed to tackle the...
The efficacy of vaccines against major encapsulated bacterial pathogens – Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae type b (Hib) – has been significantly...
We conducted two studies in Africa to evaluate a new MenA conjugate vaccine (PsA-TT). In study A, 601 children, 12 to 23 months of age, were randomly assigned to receive PsA-TT, a quadrivalent...
Acute bacterial meningitis (ABM) is a major cause of illness and death in children in sub-Saharan Africa. Neisseria meningitidis is the most common cause of ABM in the meningitis belt (sub-Saharan...
The introduction of Haemophilus influenzae type b (Hib) conjugate vaccines has greatly reduced the incidence of invasive Hib disease. However, concern exists about the possible emergence of \"strain...
This study assesses the cost-effectiveness of introducing pneumococcal polysaccharide and nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) in the National Immunization...
Suspected and unexpected clinical features of pathogens might only become apparent during clinical trials to test vaccines or after implementation of vaccination programmes. For example, the role of...
This 2015 Pneumonia and Diarrhea Progress Report evaluates the progress of the 15 countries with the greatest burden of under-five pneumonia and diarrhea
deaths in implementing high-impact...
In the past few years, new and underutilized vaccines against diseases associated with high disease burden in developing countries such as Streptococcus pneumoniae, Haemophilus influenzae type b...
The Royal Society convened a meeting on the 17th and 18th November 2010 to review the current ways in which vaccines are developed and deployed, and to make recommendations as to how each of these...
Three bacteria—Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitidis—account for most acute bacterial meningitis. Measurement of the effect of protein-polysaccharide...
Experiments almost 20 years ago demonstrated that injections of a sequence of DNA encoding part of a pathogen could stimulate immunity. It was soon realized that \"DNA vaccination\" had numerous...