Guidance

LC16m8 (live-attenuated freeze-dried vaccinia) smallpox and mpox vaccine - Interim Guidance

This first version of the interim guidance is primarily intended for use by health authorities, health workers, and other stakeholders involved in mpox vaccination and logistics for the deployment of the LC16m8 mpox vaccine in the Democratic Republic of the Congo (DRC) and other countries, as relevant.

Publication year

2025

Type

Guidance

Categories

  • Vaccines & delivery devices

Diseases

  • Mpox
  • Smallpox

Countries

  • Democratic Republic Of The Congo

Organisations

  • World Health Organization (WHO)

Tags

  • Outbreak

WHO Regions

  • African Region

Mpox-Policy

You can find more information about "Mpox-Policy" in the following Hot Topics:

TitleAuthorYearTypeLanguage
Smallpox and mpox (orthopoxviruses): WHO position paperWorld Health Organization (WHO)2024GuidanceEnglish, French
Summary of WHO SAGE recommendations for mpox vaccines, including considerations for off-label useWorld Health Organization (WHO)2025PresentationEnglish
Off-label vaccine use: explanatory note for countriesWorld Health Organization (WHO)2024GuidanceEnglish
MVA-BN (‎Modified Vaccinia Ankara – Bavarian Nordic)‎ smallpox and mpox vaccine: Interim guidanceWorld Health Organization (WHO)2024GuidanceEnglish, French
ETF statement on the use of Imvanex for the prevention of mpox in children below 12 years of ageEuropean Medicines Agency2024GuidanceEnglish
Regulatory & Policy Considerations for Mpox Vaccines in African CountriesWorld Health Organization (WHO), European Medicines Agency, Bavarian Nordic2025PresentationEnglish
LC16m8 (live-attenuated freeze-dried vaccinia) smallpox and mpox vaccine - Interim GuidanceWorld Health Organization (WHO)2025GuidanceEnglish, French
Frequently Asked Questions (FAQ) on use of fractional dosing with intradermal administration of mpox MVA-BN vaccine in the context of vaccine supply-constrained outbreak responseWorld Health Organization (WHO)2025GuidanceEnglish

Added by: Miluka Gunaratna

Added on: 2025-04-29 15:12:38

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Final_LC16m8_mpox_WHO_interim guidance_22April2025.pdf

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