Guidance

Smallpox and mpox (orthopoxviruses): WHO position paper

This position paper is concerned with vaccines and vaccination against mpox and smallpox. Since the publication of the 2014 meeting report on smallpox vaccines, and the 2022 interim guidance on mpox vaccines and immunization, there have been reported changes in the epidemiology of mpox, particularly in endemic settings, and new evidence has emerged regarding effectiveness, safety and public health benefits of vaccines. This document replaces the 2022 interim guidance on mpox vaccination and the 2014 meeting report on smallpox vaccines and smallpox vaccination. It contains off-label recommendations.

Publication year

2024

Type

Guidance

Categories

  • Vaccines & delivery devices

Diseases

  • Mpox
  • Smallpox

Organisations

  • World Health Organization (WHO)

Mpox-Policy

You can find more information about "Mpox-Policy" in the following Hot Topics:

TitleAuthorYearTypeLanguage
Smallpox and mpox (orthopoxviruses): WHO position paperWorld Health Organization (WHO)2024GuidanceEnglish, French
Summary of WHO SAGE recommendations for mpox vaccines, including considerations for off-label useWorld Health Organization (WHO)2025PresentationEnglish
Off-label vaccine use: explanatory note for countriesWorld Health Organization (WHO)2024GuidanceEnglish
MVA-BN (‎Modified Vaccinia Ankara – Bavarian Nordic)‎ smallpox and mpox vaccine: Interim guidanceWorld Health Organization (WHO)2024GuidanceEnglish, French
ETF statement on the use of Imvanex for the prevention of mpox in children below 12 years of ageEuropean Medicines Agency2024GuidanceEnglish
Regulatory & Policy Considerations for Mpox Vaccines in African CountriesWorld Health Organization (WHO), European Medicines Agency, Bavarian Nordic2025PresentationEnglish
LC16m8 (live-attenuated freeze-dried vaccinia) smallpox and mpox vaccine - Interim GuidanceWorld Health Organization (WHO)2025GuidanceEnglish, French
Frequently Asked Questions (FAQ) on use of fractional dosing with intradermal administration of mpox MVA-BN vaccine in the context of vaccine supply-constrained outbreak responseWorld Health Organization (WHO)2025GuidanceEnglish

Added by: Géraldine Nemrod

Added on: 2024-11-19 14:59:31

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