• Evidence base prompts changes to global policy for vaccine refrigerators

    A month ago a document titled Power Quality Challenges in LMICs - Data and Analysis was posted here on Technet Forum. Unfortunately, there has not been much feedback.  I am disappointed in the lack of discussion because in my view this study presents findings which support changes in global policy for vaccine refrigerators. The paper presents data from two representative countries on the availability and quality of electric power that are major determinants of the performance of vaccine refrigerators. The data suggest that, in both countries, the variability and intermittent supply of electric power indicates that three features are needed, universally to assure continuous, correct refrigerated storage:

    • Holdover passive cooling 
    • Integral voltage stabilizers
    • Remote temperature and power monitoring

    Consider these three issues as a basis for discussion.

     

    Hold-over passive cooling

    The period of ‘safe’...

    Evidence base prompts changes to global policy for vaccine refrigerators

    A month ago a document titled Power Quality Challenges in LMICs - Data and Analysis was posted here on Technet Forum. Unfortunately, there has not been much feedback.  I am disappointed in the lack of discussion because in my view this study presents findings which support changes in global policy for vaccine refrigerators. The paper presents data from two representative countries on the availability and quality of electric power that are major determinants of the performance of vaccine refrigerators. The data suggest that, in both countries, the variability and intermittent supply of electric power indicates that three features are needed, universally to assure continuous, correct refrigerated storage:

    • Holdover passive cooling 
    • Integral voltage stabilizers
    • Remote temperature and power monitoring

    Consider these three issues as a basis for discussion.

     

    Hold-over passive cooling

    The period of ‘safe’ vaccine storage when power is interrupted is boosted for vaccine storage by an ‘ice-lining’ that is charged with cooling when power supply is on or when sun is shining and then provides cooling when the power is cut. The data show that interruptions of the grid supply are variable and unpredictable. So a universal policy to provide a holdover of 120 hours might replace the current standards. The holdover capacity in hours remaining could be displayed on the refrigerator to inform the user of the security of stored vaccines.

     

    Integral voltage stabilizers

    Voltage stabilizers markedly increased the percent of usable electricity supply in all refrigerators monitored during the study, both those with widely varying voltages and those with frequent variations. At present, stabilizers may be supplied as separate accessories ‘bundled’ with refrigerator purchase or they may be provided within the refrigerator product. Incorporating stabilizers universally into vaccine refrigerators could benefit repair and maintenance and would assure that sensors were correctly installed,

    Remote monitoring of temperature and power

    The paper describes the system of power recording that was adopted in this study. Analysis of this data has, for the first time in over 30 years, informed manufacturers, vaccine managers and international stakeholders. Power data, when used in conjunction with temperature alarm data and vaccine management should be routinely monitored by an LMIS. The collection, transmission, analysis and dissemination of information by countries should become universal.

     

    The WHO PQS Specification Working Group might plan a discussion on the implications of this paper for the future of a universal vaccine refrigerator specification for all countries. The benefits of a universal vaccine refrigerator might be:

    • A single simple standard for all vaccine refrigerators
      • Rejecton of domestic refrigerators
      • Hybrid use of solar and grid electricity 
    • Oversight of the implementation by National Regulatory Authorities
    • Larger market, concentrated on a single universal standard
      • Better prices
      • More manufacturer interest
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