Human papillomavirus vaccines: WHO position paper, December 2022

This document replaces the 2014 WHO position paper on vaccines against diseases caused by human papillomaviruses (HPV). It focuses primarily on the prevention of cervical cancer, but also considers the broader

spectrum of cancers and other diseases preventable by HPV vaccination. It incorporates recent developments

concerning HPV vaccines, including the licensure of a nonavalent (9-valent) vaccine and recent data on vaccine

effectiveness, and provides guidance on the choice of vaccine. New recommendations are proposed regarding

vaccination strategies targeting girls only or both girls and boys, and vaccination of multiple birth cohorts. These recommendations were discussed by SAGE in October 2016. Evidence presented at the SAGE meeting can be accessed at:



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  • Service delivery

Topic references


Guide to introducing HPV vaccine into national immunization programmesWorld Health Organization (WHO)2016GuidancePortuguese
HPV Vaccine Communication: Special considerations for a unique vaccineChristine McNab, Susan Wang, Tracey GoodmanGuidanceEnglish
HPV Vaccine Introduction Clearing HouseWorld Health Organization (WHO)1960RepositoryEnglish
Human papillomavirus vaccines: WHO position paper, December 2022World Health Organization (WHO)GuidanceArabic, Chinese, English, French, Russian, Spanish
Lier les interventions sanitaires à l’intention des adolescents avec la vaccination anti-PVH : différentes optionsOMS - Organisation Mondiale de la Santé2014GuidanceEnglish, French, Russian, Spanish
Options for linking health interventions for adolescents with HPV vaccinationWorld Health Organization (WHO)2014GuidanceEnglish, French, Russian, Spanish
PRIME cost effectiveness toolWorld Health Organization (WHO)ToolEnglish
Scaling-up HPV vaccine introductionWorld Health Organization (WHO)2016GuidanceEnglish, French
WHO Cervical Cancer Prevention and Control Costing Tool (C4P)World Health Organization (WHO)ToolEnglish, French

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Added on: 2017-05-19 12:12:05

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