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GPEI – a brief review of 2023 and full focus on 2024 The Global Polio Eradication Initiative has two goals laid out in its current strategy: to interrupt all remaining transmission of endemic wild poliovirus type 1 (WPV1) and to stop all outbreaks of variant poliovirus type 2 (cVDPV2). 2023 was a critical year for p...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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6 minute read JANUARY 3, 2024 IN THIS ISSUE Message from the Executive Director Newly Released: AIRA 2023 Annual Report You’re Invited to Participate in M&I’s Latest Content Area SnapShots December Edition The PPW Is Here for You Mark Your Calendars for the January Discovery Session New Year, New Opportuniti...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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Global Polio Partners, Paris Saint-Germain Endowment Fund, and the French Gaming Community Unite to #ENDPOLIO On 5th December the French gaming community made a call for collective action to defeat a common adversary – only it was not an online gaming threat, but poliovirus. Read more in the latest issue of th...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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5 minute read DECEMBER 20, 2023 IN THIS ISSUE 'Tis the Season to Register for #AIRA2024 Mark Your Calendars for the January Discovery Session Information Requests SnapShots December Edition Need Help Publishing? New HL7 Patient-Matching Reports Released in AART In Case You Missed It: Check Out the Power BI Tip of the Month – Using Too...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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Wishing you a happy and peaceful holiday season🎄 ...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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8 minute read DECEMBER 13, 2023 IN THIS ISSUE Mark Your Calendars for the January Discovery Session Register Now for #AIRA2024 Information Requests New HL7 Patient Matching Reports Released in AART! Power BI Tip of the Month: Using Tooltips to Their Fullest Potential Now Available! Additional Provider Onboarding Templates for Jurisdictional ...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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29th meeting of the Regional Certification Commission on Polio Eradication in Western Pacific Region The 29th meeting of the Regional Commission for Certification (RCC) of Poliomyelitis Eradication in Western Pacific convened on 28-30 November 2023 in Manila, Philippines Read more in the latest issue of the bu...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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5 minute read DECEMBER 6, 2023 IN THIS ISSUE Message from the Executive Director Register Now for #AIRA2024 Join AIRA at HIMSS24 in Orlando Information Requests Now Available! Additional Provider Onboarding Templates for Jurisdictional Use Greetings and happy holidays! It’s hard to believe we are getting ready to w...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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!-- !- e Volume 17, Issue 11 - November 2023 The Measles and Rubella Bulletin is a monthly publication reporting progress towards achieving measles and rubella elimination in the Western Pacific Region. Inside each issue, we present the latest reported data by country on measles and rubella incidence, surveillance performance, ...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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!-- !- e Volume 17, Issue 11 - November 2023 The Measles and Rubella Bulletin is a monthly publication reporting progress towards achieving measles and rubella elimination in the Western Pacific Region. Inside each issue, we present the latest reported data by country on measles and rubella incidence, surveillance performance, ...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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EYE Strategy October newsletter Yellow fever vaccination campaign, Cameroon. May 2022 News release: EYE Strategy mid-term evaluation report Since 2017, according to EYE Strategy data, 248* million more people in Africa have been protected via yellow fever campaigns via a single-dose vaccine that provides...Post is under moderationStream item published successfully. Item will now be visible on your stream.
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Evidence of Extended Thermo-Stability of Typhoid Polysaccharide Conjugate Vaccines
Typhoid conjugate vaccines (TCV) are effective in preventing enteric fever caused by Salmonella enterica serovar Typhi in Southeast Asia and Africa. To facilitate vaccination with the Vi capsular polysaccharide–tetanus toxoid conjugate vaccine, Typbar TCV, and allow it to be transported and stored outside a cold chain just prior to administration, an extended controlled-temperature conditions (ECTC) study was performed to confirm the quality of the vaccine at 40 °C for 3 days at the end of its shelf-life (36 months at 2–8 °C). Studies performed in parallel by the vaccine manufacturer, Bharat Biotech International Limited, and an independent national control laboratory (NIBSC) monitored its stability-indicating parameters: O-acetylation of the Vi polysaccharide, integrity of the polysaccharide–protein conjugate, and its molecular size and pH. ECTC samples stored at 40 °C and 45 °C in comparison with control samples stored at 4 °C and 55 or 56 °C, were shown to have stable O-acetylation and pH; only very slight increases in the percentage of free saccharide and corresponding decreases in molecular size were observed. The deoxycholate method for precipitating conjugated polysaccharide was very sensitive to small incremental increases in percentage of free saccharide, in line with storage temperature and duration. This extended ECTC study demonstrated minimal structural changes to the Vi polysaccharide and conjugate vaccine and a stable formulation following extended exposure to elevated temperatures for the desired durations. This outcome supports the manufacturer’s ECTC claim for the vaccine to be allowed to be taken outside the cold chain before its administration.
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