Journal article

Economic benefits of keeping vaccines at ambient temperature during mass vaccination: the case of Meningitis A vaccine in Chad

The subject of the present study was a mass campaign against meningitis A that covered three regions of Chad and resulted in the vaccination of 1 807 158 individuals in December 2011. Although 12 districts, 668 fixed health posts, 287 outreach posts and 55 mobile teams implemented the campaign, the infrastructure supporting the CCL system used throughout the campaign was weak.8 The campaign therefore provided a good case study for exploring the benefits of CTC. The main aim of the present study was to model the economic benefits that could have been obtained had the vaccine used in this campaign been kept at or near ambient temperatures at the peripheral levels of the supply chain system. The flexibility offered by being able to keep vaccines in a CTC at the periphery could have far-reaching benefits, especially for the 450 million people at risk of meningitis who live in the African “meningitis belt”.

Languages

  • English

Publication year

2014

Journal

Bulletin of the World Health Organization

Volume

92

Type

Journal article

Categories

  • Supply chain & logistics

Diseases

  • Meningococcal meningitis

Countries

  • Chad

Organisations

  • World Health Organisation (WHO)

Tags

  • Controlled temperature chain (CTC)
  • Distribution system
  • MenAfriVac

WHO Regions

  • African Region

Topic references

CTC_JOURNAL

TitleAuthorYearTypeLanguage
A cluster randomized non-inferiority field trial on the immunogenicity and safety of tetanus toxoid vaccine kept in controlled temperature chain compared to cold chainRebecca F. Grais, Primitive Gakima, Paul Baoundoh, Mbaihol Tamadji, Martha H. Roper, Florence Fermon, Céline Langendorf, Camille Domicent, Aitana Juan-Giner, Simona Zipursky2014Journal articleEnglish
A field based evaluation of adverse events following MenAfriVac® vaccine delivered in a controlled temperature chain (CTC) approach in Benin Christoph Steffen, Evariste Tokplonou, Philippe Jaillard, Roger Dia, Marie N Deye Bassabi Alladji, Bradford Gessner2014Journal articleEnglish
An economic evaluation of the controlled temperature chain approach for vaccine logistics: evidence from a study conducted during a meningitis A vaccine campaign in TogoMercy Mvundura, Patrick Lydon, Abdoulaye Gueye, Ibnou Khadim Diaw, Dadja Essoya Landoh, Bafei Toi, Anna-Lea Kahn, Debra Kristensen2017Journal articleEnglish
Antivenoms, hepatitis B vaccine and oral polio vaccine can be considered for storage and handling outside the cold chain following the innovative 'controlled temperature chain' approachShereen H. Mohamed, Osama A. Hady, Mona T. Kashef, Hamdallah Zedan2022Journal articleEnglish
Benefits of using vaccines out of the cold chain: Delivering Meningitis A vaccine in a controlled temperature chain during the mass immunization campaign in BeninSimona Zipursky, Mamoudou Harouna Djingarey, Jean-Claude Lodjo, Laifoya Olodo, Sylvestre Tiendrebeogo, Olivier Ronveaux2014Journal articleEnglish
Can thermostable vaccines help address cold-chain challenges? Results from stakeholder interviews in six low- and middle-income countriesDebra D. Kristensen, Tina Lorenson, Kate Bartholomew, Shirley Villadiego2016Journal articleEnglish
Cost-effectiveness of the controlled temperature chain for the hepatitis B virus birth dose vaccine in various global settings: a modelling studyNick Scott, Anna Palmer, Christopher Morgan, Olufunmilayo Lesi, Wendy Spearman, Mark Sonderup, Margaret Hellard2018Journal articleEnglish
Countries’ interest in a hepatitis B vaccine licensed for the controlled temperature chain; survey results from African and Western Pacific regionsDörte Petit, Carole Tevi-Benissan, Joseph Woodring, Karen Hennessey, Anna-Lea Kahn2017Journal articleEnglish
Economic benefits of keeping vaccines at ambient temperature during mass vaccination: the case of Meningitis A vaccine in ChadPatrick Lydon et al.2014Journal articleEnglish
Evidence of Extended Thermo-Stability of Typhoid Polysaccharide Conjugate VaccinesFang Gao, Alastair Logan, Sarah Davis, Barbara Bolgiano, Sjoerd Rijpkema, Gopal Singh, Sai D. Prasad, Samuel Pradeep Dondapati, Gurbaksh Singh Sounkhla2021Journal articleEnglish
Extending supply chains and improving immunization coverage and equity through controlled temperature chain use of vaccinesRaja Rao, Debra Kristensen, Anna-Lea Kahn2017Journal articleEnglish
Impact of Controlled Temperature Chain (CTC) approach on immunization coverage achieved during the preventive vaccination campaign against meningitis A using MenAfriVac in Togo in 2014Dadja Essoya Landoh, Anna-Lea Kahn, Anani Lacle, Kodjovi Adjeoda, Bayaki Saka, Issifou Yaya, Danladi Ibrahim Nassoury, Assima Kalao, Makawa-Sy Makawa, Nsiari-Mueyi Joseph Biey, Andre Bita, Yaovi Temfa Toke, Petit Dörte, Lucile Imboua, Olivier Ronveaux2017Journal articleEnglish
Use of controlled temperature chain and compact prefilled auto-disable devices to reach 2030 hepatitis B birth dose vaccination targets in LMICs: a modelling and cost-optimisation studyChristopher P. Seaman, Christopher Morgan, Jess Howell, Yinzong Xiao, Wendy Spearman, Mark Sonderup2020Journal articleEnglish
Using human papillomavirus (HPV) vaccine in controlled temperature chain (CTC): A solution looking for a problem? Or a solution to problems that are not systematically documented?Dijana Spasenoska, Paul Bloem, Hiroki Akaba, Anna-Lea Kahn2024Journal articleEnglish

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